McAfee Virtual Advanced Threat Defense is a 64-bit virtual software version of the on-premise McAfee Advanced Threat Defense software that facilitates detection and prevention of malware. The files are first checked for known malware, then run in a sandbox environment. The sandbox provides a controlled environment where Network access is usually disallowed or heavily restricted. You can deploy it on a VMware ESXi virtual machine environment. Once the virtual appliance is deployed and set up, you can manage McAfee Virtual Advanced Threat Defense through its web-interface in a browser from your management computer.